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Browse Mutations mcr-1P198Y

colistin resistance protein

Protein ChangeP198Y

Nucleotide ChangeC592T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Colistin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience.

PMID 37071007 · 2023

mutations affect MCR-1 stability and activity

Mutation Information

mcr-1: p.P198Y / c.C592T

Protein Change: P198Y
Nucleotide Change: C592T
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Colistin

Source Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research