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Browse Mutations parEH103Y

GeneparE

Protein ChangeH103Y

Nucleotide ChangeCAT->TAT

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Moxifloxacin|Sparfloxacin|Grepafloxacin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

ATP-bound conformation of topoisomerase IV: a possible target for quinolones in Streptococcus pneumoniae.

PMID 14526026 · 2003

The His103Tyr mutation was found to confer resistance to fluoroquinolones when associated with a mutation in the QRDR of GyrA.

Mutation Information

parE: p.H103Y / c.CAT->TAT

Protein Change: H103Y
Nucleotide Change: CAT->TAT
Organisms: Streptococcus pneumoniae

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Confers Resistance To

Moxifloxacin|Sparfloxacin|Grepafloxacin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research