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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations blaNDMM154V

beta-lactamase

Protein ChangeM154V

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: enhances Zn(II) binding affinity
Resistance To: Carbapenem|Penicillin|Cephalosporin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Clinical Evolution of New Delhi Metallo-β-Lactamase (NDM) Optimizes Resistance under Zn(II) Deprivation.

PMID 29038264 · 2018

Mutations in blaNDM were analyzed for their impact on Zn(II) binding and resistance.

Mutation Information

blaNDM: p.M154V

Protein Change: M154V
Organisms: Escherichia coli
Confers Resistance To: Carbapenem|Penicillin|Cephalosporin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

enhances Zn(II) binding affinity

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research