Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency.
Mutations in the rpoB gene were identified through sequencing of gene fragments.
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Nanopore-based targeted next-generation sequencing (tNGS): A versatile technology specialized in detecting low bacterial load clinical specimens.
All mutations were identified in the rpoB gene, with 20 located in the rifampicin resistance-determining region (RRDR) and one outside the RRDR.
Molecular profiling of drug resistant isolates of Mycobacterium tuberculosis in the state of Santa Catarina, southern Brazil.
Mutations in rpoB are associated with rifampicin resistance.
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