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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations pbp3Y721S

Genepbp3

penicillin-binding protein

Protein ChangeY721S

Nucleotide ChangeG2162C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Carbapenem, Imipenem
Organisms: Clostridium difficile
Papers: 2

Paper Information2

1

A species-wide genetic atlas of antimicrobial resistance in Clostridioides difficile.

PMID 34793295 · 2021

Mutation associated with carbapenem resistance

Mutation Information

Protein Change: Y721S
Confers Resistance To: Carbapenem

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal.

PMID 29553322 · 2018

Mutation in pbp3 gene

Mutation Information

pbp3: p.Y721S / c.G2162C

Protein Change: Y721S
Nucleotide Change: G2162C
Organisms: Clostridium difficile
Confers Resistance To: Imipenem
Source Database: Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research