ResLit - Antimicrobial Resistance Gene & Mutation Database

GenekatG

Protein ChangeM257I

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis isolates collected in Australia.

PMID 16189082 · 2005

Three novel katG mutations (D117A, M257I, G491C) were identified in three INH-resistant strains with a wild-type katG codon 315, fabG1-inhA regulatory region, and inhA structural gene.

Mutation Information

katG: p.M257I

Protein Change: M257I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Isoniazid
Source Database: Reslit

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