GeneparE
Protein ChangeS458T
Nucleotide ChangeTCA -> ACC
Validation StatusConfirmed2+ DBs
Databases
ResFinderReslit
Overview
- Mechanism
- Target modification
- Resistance To
- norfloxacin|ciprofloxacin, Nalidixic acid,Ciprofloxacin
- Organisms
- Escherichia coli
- Papers
- 2
Paper Information2
1
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
Unknown phenotype if S458T or S458A occur alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mutation Information
- Protein Change
- S458T
- Nucleotide Change
- TCA -> ACC
- Organisms
- Escherichia coli
- Confers Resistance To
- norfloxacin|ciprofloxacinNalidixic acid,Ciprofloxacin
- Effect on Function
- Target modification
- Source Database
- ReslitResFinder
2
Avoiding perforation during endodontic access.
Unknown phenotype if S458T or S458A occur alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mutation Information
- Protein Change
- S458T
- Organisms
- Escherichia coli
- Confers Resistance To
- Nalidixic acid,Ciprofloxacin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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