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Browse Mutations rplCY89H

GenerplC

Protein ChangeY89H

Nucleotide ChangeT265C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Pretomanid
Papers: 1

Paper Information1

1

Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria.

PMID 32456032 · 2020

Mutations in rplC and ddn genes confer resistance to linezolid and pretomanid, respectively.

Mutation Information

rplC: p.Y89H / c.T265C

Protein Change: Y89H
Nucleotide Change: T265C
Confers Resistance To: Pretomanid

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research