GeneparE
Protein ChangeH103Y
Nucleotide ChangeCAT->TAT
Validation StatusCandidate
Databases
Reslit
Overview
- Resistance To
- moxifloxacin|sparfloxacin|grepafloxacin
- Organisms
- Streptococcus pneumoniae
- Papers
- 1
Paper Information1
1
ATP-bound conformation of topoisomerase IV: a possible target for quinolones in Streptococcus pneumoniae.
The His103Tyr mutation was found to confer resistance to fluoroquinolones when associated with a mutation in the QRDR of GyrA.
Mutation Information
- Protein Change
- H103Y
- Nucleotide Change
- CAT->TAT
- Organisms
- Streptococcus pneumoniae
- Confers Resistance To
- moxifloxacin|sparfloxacin|grepafloxacin
- Source Database
- Reslit
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