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Browse Mutations rpoBI70M

GenerpoB

Protein ChangeI70M

Nucleotide ChangeG212C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Rifampicin
Organisms: Mycobacterium smegmatis, Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

A CRISPR-guided mutagenic DNA polymerase strategy for the detection of antibiotic-resistant mutations in M. tuberculosis.

PMID 35950213 · 2022

Mutation I70M in rpoB was confirmed to confer rifampicin resistance.

Mutation Information

rpoB: p.I70M / c.G212C

Protein Change: I70M
Nucleotide Change: G212C
Organisms: Mycobacterium smegmatis, Mycobacterium tuberculosis

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Confers Resistance To

Rifampicin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research