Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins.
Mutations in penA contribute to β-lactam resistance in Neisseria spp.
penA
Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.
Mutations in penA are critical for intermediate resistance to expanded-spectrum cephalosporins in Neisseria gonorrhoeae.
Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity.
Mutations in penA confer resistance to ceftriaxone and cefixime
WGS to predict antibiotic MICs for Neisseria gonorrhoeae.
Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally.
Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state.
All mutations are in the β3–β4 loop of PBP2 and contribute to ceftriaxone resistance by altering the conformational dynamics of the protein.
Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates.
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.
Associated with decreased susceptibility to cefixime and ceftriaxone.
Mutation indicates mosaic penA gene
Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.
mutations in penA are critical for resistance to ceftriaxone and cefixime
Antibiotic Resistance in Neisseria gonorrhoeae: Challenges in Research and Treatment.
Mutations in penA are associated with ceftriaxone resistance.
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