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Browse Mutations mtrEN198L

GenemtrE

outer membrane porin

Protein ChangeN198L

Nucleotide ChangeAAC->CTC

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Vancomycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner.

PMID 21115481 · 2011

Mutations in the intra-protomer groove of MtrE lead to increased susceptibility to antibiotics.

Mutation Information

mtrE: p.N198L / c.AAC->CTC

Protein Change: N198L
Nucleotide Change: AAC->CTC
Organisms: Escherichia coli

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Confers Resistance To

Vancomycin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research