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Browse Mutations mtrCE149C

GenemtrC

efflux pump

Protein ChangeE149C

Nucleotide ChangeG447T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Tetracycline|Vancomycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3.

PMID 21610073 · 2011

Cysteine insertion in the hairpin domain of MtrC affects pump function.

Mutation Information

mtrC: p.E149C / c.G447T

Protein Change: E149C
Nucleotide Change: G447T
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Tetracycline|Vancomycin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research