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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations pbp2xS394A

penicillin-binding protein 2X

Protein ChangeS394A

Nucleotide ChangeT1180C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Ampicillin|Penicillin|Cefotaxime|Ceftriaxone|Cefuroxime|Cefaclor
Papers: 1

Paper Information1

1

Comparative genomics study of multi-drug-resistance mechanisms in the antibiotic-resistant Streptococcus suis R61 strain.

PMID 21966396 · 2011

Mutations in the active site of PBP2x contribute to β-lactam resistance.

Mutation Information

pbp2x: p.S394A / c.T1180C

Protein Change: S394A
Nucleotide Change: T1180C
Confers Resistance To: Ampicillin|Penicillin|Cefotaxime|Ceftriaxone|Cefuroxime|Cefaclor

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research