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Browse Mutations yybTI440S

GeneyybT

peptide permease

Protein ChangeI440S

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: cyclic dinucleotide phosphodiesterase YybT, single resistance variant
Resistance To: DAPTOMYCIN, Daptomycin
Organisms: Enterococcus faecalis
Papers: 1

Paper Information1

1

Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance.

PMID 23959318 · 2013

Enterococcus faecalis YybT with mutation conferring daptomycin resistance; CARD accession: CARD:3003797

Mutation Information

Protein Change: I440S
Organisms: Enterococcus faecalis
Confers Resistance To: Daptomycin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research