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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations liaSH264Q

GeneliaS

two-component system histidine kinase

Protein ChangeH264Q

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: sensor histidine kinase LiaS, single resistance variant
Resistance To: DAPTOMYCIN, Daptomycin
Organisms: Enterococcus faecium
Papers: 1

Paper Information1

1

Correlation between mutations in liaFSR of Enterococcus faecium and MIC of daptomycin: revisiting daptomycin breakpoints.

PMID 22664970 · 2012

Enterococcus faecium liaS mutant conferring daptomycin resistance; CARD accession: CARD:3003079

Mutation Information

Protein Change: H264Q
Organisms: Enterococcus faecium
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Daptomycin

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research