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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoBS531fs

GenerpoB

Protein ChangeS531fs

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: frameshift mutation
Resistance To: Rifampicin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Antibiotic resistance by high-level intrinsic suppression of a frameshift mutation in an essential gene.

PMID 31992637 · 2020

Escherichia coli rpoB mutants conferring resistance to rifampicin; CARD accession: CARD:3003288

Mutation Information

Protein Change: S531fs
Organisms: Escherichia coli
Confers Resistance To: Rifampicin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

frameshift mutation

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research