ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD472H

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: co-dependent single resistance variant
Resistance To: Fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Novel gyrase mutations in quinolone-resistant and -hypersusceptible clinical isolates of Mycobacterium tuberculosis: functional analysis of mutant enzymes.

PMID 16377674 · 2006

Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003295

Mutation Information

gyrA: p.D472H

Protein Change: D472H
Organisms: Mycobacterium tuberculosis
Confers Resistance To

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Mutation Information