ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemshA

mycothiol synthase

Protein ChangeF355S

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Prothionamide, Isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Detection of novel mutations associated with independent resistance and cross-resistance to isoniazid and prothionamide in Mycobacterium tuberculosis clinical isolates.

PMID 30583053 · 2019

Mycobacterium tuberculosis mshA mutations conferring resistance to prothionamide; CARD accession: CARD:3005108

Mycobacterium tuberculosis mshA mutations conferring resistance to isoniazid; CARD accession: CARD:3004925

Mutation Information

mshA: p.F355S

Protein Change: F355S
Organisms

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Mutation Information