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Browse Mutations ndhA300P

Genendh

NADH dehydrogenase

Protein ChangeA300P

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Detection of mutations associated with isoniazid resistance in multidrug-resistant Mycobacterium tuberculosis clinical isolates.

PMID 24855126 · 2014

Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid; CARD accession: CARD:3003461

Mutation Information

Protein Change: A300P
Organisms: Mycobacterium tuberculosis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Isoniazid

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research