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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoCG1122D

GenerpoC

Protein ChangeG1122D

Nucleotide ChangeG3365A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Cefuroxime, RIF
Organisms: Bacillus subtilis
Papers: 2

Paper Information2

1

A mutation of the RNA polymerase β′ subunit (rpoC) confers cephalosporin resistance in Bacillus subtilis.

PMID 23070162 · 2013

Mutation Information

rpoC: p.G1122D / c.G3365A

Protein Change: G1122D
Nucleotide Change: G3365A
Organisms: Bacillus subtilis
Confers Resistance To: Cefuroxime

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

A mutation in RNA polymerase imparts resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism.

PMID 39908144 · 2025

Mutation Information

Protein Change: G1122D
Organisms: Bacillus subtilis
Confers Resistance To: RIFCefuroxime
Source Database: Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research