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Browse Mutations tapT297P

Genetap

efflux pump

Protein ChangeT297P

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Ethambutol & Capreomycin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Rv1258c acts as a drug efflux pump and growth controlling factor in Mycobacterium tuberculosis.

PMID 35158297 · 2022

Mycobacterium tuberculosis Rv1258c mutations confer resistance to ethambutol and capreomycin; CARD accession: CARD:3007185

Mutation Information

Protein Change: T297P
Organisms: Mycobacterium tuberculosis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Ethambutol & Capreomycin

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research