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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations ndhR202W

Genendh

NADH dehydrogenase

Protein ChangeR202W

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

PMID 15673755 · 2005

Mycobacterium tuberculosis variant bovis ndh with mutation conferring resistance to isoniazid; CARD accession: CARD:3003779

Mutation Information

Protein Change: R202W
Organisms: Mycobacterium tuberculosis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Isoniazid

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research