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Browse Mutations rrlc2641a

Generrl

23S rRNA

Nucleotide Changec2641a

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Macrolides
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.

PMID 10898684 · 2000

Streptococcus pneumoniae 23S rRNA with mutation conferring resistance to macrolide antibiotics; CARD accession: CARD:3004170

Mutation Information

Nucleotide Change: c2641a
Organisms: Streptococcus pneumoniae
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Macrolides

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research