Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations rpoCQ781R

GenerpoC

Protein ChangeQ781R

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoC
Resistance To: FIDAXOMICIN
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

1

Killing kinetics of fidaxomicin and its major metabolite, OP-1118, against Clostridium difficile.

PMID 21349983 · 2011

rpoC

Mutation Information

Protein Change: Q781R
Organisms: Clostridioides difficile
Confers Resistance To: FIDAXOMICIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

DNA-directed RNA polymerase subunit beta RpoC

Source Database

Reference Gene Catalog

Comments (0)

No comments yet. Be the first to comment!

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research