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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rrlT754A

Generrl

23S rRNA

Nucleotide ChangeT754A

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: 23S ribosomal RNA, Target modification
Resistance To: ERYTHROMYCIN/TELITHROMYCIN, Erythromycin,Telithromycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre.

PMID 10027979 · 1999

23S

Mutation Information

Nucleotide Change: T754A
Organisms: Escherichia coli
Confers Resistance To: ERYTHROMYCIN/TELITHROMYCIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Erythromycin,Telithromycin

Effect on Function

23S ribosomal RNA; Target modification

Source Database

Reference Gene CatalogResFinder Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research