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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations ampCC-42A

GeneampC

beta-lactamase

Nucleotide ChangeC-42A

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: ampC/blaEC promoter region, Enzymatic degradation
Resistance To: CEPHALOSPORIN, Ampicillin, Ampicillin+clavulanic acid, Amoxicillin, Amoxicillin+clavulanic acid, Cefixime, Cefotaxime, Cefoxitin, Ceftazidime, Piperacillin
Organisms: Escherichia coli
Papers: 2

Paper Information2

1

The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation.

PMID 7010184 · 1981

ampC

Mutation Information

Nucleotide Change: C-42A
Organisms: Escherichia coli
Confers Resistance To: CEPHALOSPORIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

ampC/blaEC promoter region

Source Database

Reference Gene Catalog

2

Detection of AmpC beta-lactamase in Escherichia coli: comparison of three phenotypic confirmation assays and genetic analysis.

PMID 21653764 · 2011

ampC

Mutation Information

Nucleotide Change: C-42A
Organisms: Escherichia coli
Confers Resistance To: CEPHALOSPORINAmpicillin, Ampicillin+clavulanic acid, Amoxicillin, Amoxicillin+clavulanic acid, Cefixime, Cefotaxime, Cefoxitin, Ceftazidime, Piperacillin
Effect on Function: ampC/blaEC promoter region; Enzymatic degradation
Source Database: Reference Gene CatalogResFinder Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research