ResLit - Antimicrobial Resistance Gene & Mutation Database

GenecirA

iron transporter

Protein ChangeR86S

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: catecholate siderophore receptor CirA
Resistance To: CEFIDEROCOL
Organisms: Escherichia coli
Papers: 1

Paper Information1

Rapid selection of a cefiderocol-resistant Escherichia coli producing NDM-5 associated with a single amino acid substitution in the CirA siderophore receptor.

PMID 36864015 · 2023

cirA

Mutation Information

cirA: p.R86S

Protein Change: R86S
Organisms: Escherichia coli
Confers Resistance To: CEFIDEROCOL

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Mutation Information