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Browse Mutations nfsAR203L

GenenfsA

nitroreductase

Protein ChangeR203L

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: nitroreductase NfsA, single resistance variant
Resistance To: NITROFURANTOIN, Nitrofurantoin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli.

PMID 18544599 · 2008

nfsA

Escherichia coli nfsA mutations conferring resistance to nitrofurantoin; CARD accession: CARD:3003751

Mutation Information

Protein Change: R203L
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

NITROFURANTOIN

Nitrofurantoin

Effect on Function

nitroreductase NfsA; single resistance variant

Source Database

Reference Gene CatalogCard Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research