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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations pmrBC84Y

GenepmrB

Protein ChangeC84Y

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: two-component system sensor histidine kinase PmrB
Resistance To: Colistin, COLISTIN
Organisms: E. coli, Escherichia coli
Papers: 2

Paper Information2

1

Acquisition of the mcr-1 Gene Lowers the Target Mutation to Impede the Evolution of a High-Level Colistin-Resistant Mutant in Escherichia coli.

PMID 34408448 · 2021

Mutation Information

Protein Change: C84Y
Organisms: E. coli
Confers Resistance To: Colistin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

Colistin resistance in Parisian inpatient faecal Escherichia coli as the result of two distinct evolutionary pathways.

PMID 30863849 · 2019

pmrB

Mutation Information

Protein Change: C84Y
Organisms: Escherichia coli
Confers Resistance To: COLISTIN
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research