ResLit - Antimicrobial Resistance Gene & Mutation Database

GenenfxB

transcriptional repressor of MexCD-OprJ efflux pump

Protein ChangeR42H

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: efflux pump transcriptional repressor NfxB
Resistance To: COLISTIN
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Cross-resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps: exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ.

PMID 11158736 · 2001

nfxB

Mutation Information

nfxB: p.R42H

Protein Change: R42H
Organisms: Pseudomonas aeruginosa
Confers Resistance To

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Mutation Information