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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations penAG482S

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeG482S

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduced reactivity for β-lactams
Resistance To: Ceftriaxone|Cefixime
Organisms: Neisseria gonorrhoeae, Neisseria meningitidis
Papers: 1

Paper Information1

1

Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins.

PMID 27690121 · 2016

Mutations in penA contribute to β-lactam resistance in Neisseria spp.

Mutation Information

Protein Change: G482S
Organisms: Neisseria gonorrhoeae, Neisseria meningitidis
Confers Resistance To: Ceftriaxone|Cefixime

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

reduced reactivity for β-lactams

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research