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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoBI527F

GenerpoB

Protein ChangeI527F

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB, Target modification
Resistance To: RIFAMPIN, Rifampicin
Organisms: Staphylococcus aureus
Papers: 2

Paper Information2

1

Biological cost of rifampin resistance from the perspective of Staphylococcus aureus.

PMID 12384339 · 2002

rpoB

Mutation Information

Protein Change: I527F
Organisms: Staphylococcus aureus
Confers Resistance To: RIFAMPIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

DNA-directed RNA polymerase subunit beta RpoB

Source Database

Reference Gene Catalog

2

Differential effect of rpoB mutations on antibacterial activities of rifampicin and KRM-1648 against Staphylococcus aureus.

PMID 11157898 · 2001

Mutation Information

Protein Change: I527F
Organisms: Staphylococcus aureus
Confers Resistance To: Rifampicin
Effect on Function: Target modification
Source Database: ResFinder Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research