ResLit - Antimicrobial Resistance Gene & Mutation Database

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeA501S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Cefixime|Ceftriaxone
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

PMID 28145684 · 2017

Mutations in penA gene lead to resistance to cephalosporins.

Mutation Information

penA: p.A501S

Protein Change: A501S
Organisms: Neisseria gonorrhoeae
Confers Resistance To: Cefixime|Ceftriaxone

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