Protein ChangeG238S
Validation StatusCandidate
Databases
Reslit
Overview
- Mechanism
- confers extended-spectrum beta-lactamase (ESBL) activity
- Resistance To
- ceftazidime|cefotaxime|aztreonam
- Organisms
- Klebsiella pneumoniae
- Papers
- 1
Paper Information1
1
bla(SHV) Genes in Klebsiella pneumoniae: different allele distributions are associated with different promoters within individual isolates.
Mutations in codons 238 and 240 of blaSHV contribute to extended-spectrum beta-lactamase (ESBL) activity.
Mutation Information
- Protein Change
- G238S
- Organisms
- Klebsiella pneumoniae
- Confers Resistance To
- ceftazidime|cefotaxime|aztreonam
- Effect on Function
- confers extended-spectrum beta-lactamase (ESBL) activity
- Source Database
- Reslit
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