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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations gyrBE483D

GenegyrB

Protein ChangeE483D

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Resistance To: Ciprofloxacin|Levofloxacin|Ofloxacin, QUINOLONE
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Mutations in gyrB play an important role in ciprofloxacin-resistant Pseudomonas aeruginosa.

PMID 30804676 · 2019

gyrB

Mutation Information

Protein Change: E483D
Organisms: Pseudomonas aeruginosa
Confers Resistance To: Ciprofloxacin|Levofloxacin|Ofloxacin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

QUINOLONE

Effect on Function

DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB

Source Database

ReslitReference Gene Catalog

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research