GenerpoB
Protein ChangeV146F
Validation StatusConfirmed2+ DBs
Databases
ResFinderReslit
Overview
- Mechanism
- Target modification
- Resistance To
- rifampin, rifabutin, Rifampicin
- Organisms
- Mycobacterium tuberculosis, Escherichia coli
- Papers
- 3
Paper Information3
1
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
all mutations are in the rpoB gene and confer resistance to rifampin
Mutation Information
- Protein Change
- V146F
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampin
- Source Database
- Reslit
2
Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency.
Mutations in the rpoB gene were identified through sequencing of gene fragments.
Mutation Information
- Protein Change
- V146F
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifabutin
- Source Database
- Reslit
3
Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.
Mutation Information
- Protein Change
- V146F
- Organisms
- Escherichia coli
- Confers Resistance To
- Rifampicin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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