GenerpoB
Protein ChangeD516Y
Validation StatusCandidate
Databases
Reslit

Overview

Resistance To
rifampin
Organisms
Mycobacterium tuberculosis
Papers
2
Paper Information2
1

Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.

PMID 15917513 · 2005

all mutations are in the rpoB gene and confer resistance to rifampin

Mutation Information

Protein Change
D516Y
Organisms
Mycobacterium tuberculosis
Confers Resistance To
rifampin
Source Database
Reslit
2

Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin.

PMID 19146699 · 2009

Some mutations in the rpoB gene can reveal drug-resistant phenotype only in a specific genetic background of the host.

Mutation Information

Protein Change
D516Y
Nucleotide Change
G516A
Organisms
Mycobacterium tuberculosis
Confers Resistance To
rifampin
Source Database
Reslit
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