Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Antimicrobial resistance and bacterial identification utilizing a microelectronic chip array.
Incidence and mechanism of ciprofloxacin resistance in Campylobacter spp. isolated from commercial poultry flocks in the United Kingdom before, during, and after fluoroquinolone treatment.
The Thr-86→Ile mutation in gyrA was the most common mutation associated with ciprofloxacin and nalidixic acid resistance.
Molecular evidence for the thriving of Campylobacter jejuni ST-4526 in Japan.
Single base mutation in gyrA at Thr86 plays a role in increasing the resistance of nalidixic acid (NA) and fluoroquinolones in Campylobacter.
WGS-Based Prediction and Analysis of Antimicrobial Resistance in Campylobacter jejuni Isolates From Israel.
Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data.
Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile.
This mutation confers high levels of resistance to fluoroquinolones.
Occurrence, Antimicrobial Resistance, and Molecular Characterization of Campylobacter spp. in Intensive Pig Production in South Africa.
Distribution of CRISPR Types in Fluoroquinolone-Resistant Campylobacter jejuni Isolates.
Mutations in the QRDR of gyrA are associated with fluoroquinolone resistance in C. jejuni.
High-throughput sequencing reveals genetic determinants associated with antibiotic resistance in Campylobacter spp. from farm-to-fork.
Mutations in the QRDR of gyrA confer resistance to quinolones.
Core Genome MLST for Source Attribution of Campylobacter coli.
Molecular Detection of Fluoroquinolone Resistance among Multidrug-, Extensively Drug-, and Pan-Drug-Resistant Campylobacter Species in Egypt.
Chromosomal mutation in the QRDR of the gyrA gene
Systematic Evaluation of Whole-Genome Sequencing Based Prediction of Antimicrobial Resistance in Campylobacter jejuni and C. coli.
Confers resistance to quinolones
Genomic diversity and antimicrobial resistance of Campylobacter spp. from humans and livestock in Nigeria.
Genomic Relatedness, Antibiotic Resistance and Virulence Traits of Campylobacter jejuni HS19 Isolates From Cattle in China Indicate Pathogenic Potential.
Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs.
Prevalence and genetic characteristics of Campylobacter jejuni from laying-hens in Hubei Province, China.
Genomic epidemiology and the evolution of erm(B)-mediated macrolide resistance in Campylobacter.
Confers resistance to quinolones
Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure.
The C257T mutation in gyrA confers high-level fluoroquinolone resistance and enhances in vivo fitness of Campylobacter jejuni.
Genomic Analysis Reveals the Genetic Determinants Associated With Antibiotic Resistance in the Zoonotic Pathogen Campylobacter spp. Distributed Globally.
Mutations in gyrA are associated with fluoroquinolone resistance.
Genotyping and Antibiotic Resistance Traits in Campylobacter jejuni and coli From Pigs and Wild Boars in Italy.
Antibiotic Resistance Profiles and Molecular Mechanisms of Campylobacter From Chicken and Pig in China.
Phenotypic and Molecular Patterns of Resistance among Campylobacter coli and Campylobacter jejuni Isolates, from Pig Farms.
Ongoing Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Associated With US Pet Store Puppies, 2016-2020.
Differences in Genotype and Antimicrobial Resistance between Campylobacter spp. Isolated from Organic and Conventionally Produced Chickens in Sweden.
WQ-3810, a fluoroquinolone with difluoropyridine derivative as the R1 group exerts high potency against quinolone-resistant Campylobacter jejuni.
Campylobacter coli of porcine origin exhibits an open pan-genome within a single clonal complex: insights from comparative genomic analysis.
Antimicrobial resistance and genomic characteristics of Campylobacter spp. From Australian meat chickens with A follow up investigation.
T86I mutation in the QRDR of gyrA reduces sensitivity to quinolones
Phenotypic and whole genome-based characterization of antibiotic resistance of Campylobacter jejuni isolates from chicken livers.
Point mutation in the subunit A of the DNA gyrase gene
Genomic analysis and antimicrobial resistance in human- and poultry-derived Campylobacter jejuni isolates from Hangzhou, China.
The T86I mutation was predominant, detected in 91.5% (43/47) of isolates.
Antimicrobial susceptibilities of thermophilic Campylobacter from humans, swine, and chicken broilers.
mutation in gyrA leads to quinolone resistance
Development of experimental genetic tools for Campylobacter fetus.
Mutation in gyrA leads to ciprofloxacin resistance
Clonal population structure and antimicrobial resistance of Campylobacter jejuni in chicken meat from Belgium.
Mutation in gyrA confers resistance to fluoroquinolones.
Whole Genome Sequence-Based Prediction of Resistance Determinants in High-Level Multidrug-Resistant Campylobacter jejuni Isolates in Lithuania.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
mutation in gyrA gene associated with quinolone resistance
Antimicrobial Resistance in Campylobacter coli and Campylobacter jejuni from Human Campylobacteriosis in Taiwan, 2016 to 2019.
Mutations in gyrA confer resistance to quinolones and fluoroquinolones.
Natural Horizontal Gene Transfer of Antimicrobial Resistance Genes in Campylobacter spp. From Turkeys and Swine.
Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018.
Genomic epidemiology and genetic characteristics of clinical Campylobacter species cocirculating in West Bengal, India, 2019, using whole genome analysis.
Strain sharing and mobile genetic elements shape the interconnected resistomes of Campylobacter coli in Brazil.
Characterization and Phylogenetic Analysis of Campylobacter Species Isolated from Paediatric Stool and Water Samples in the Northwest Province, South Africa.
Genomic Analysis of Emerging Florfenicol-Resistant Campylobacter coli Isolated from the Cecal Contents of Cattle in the United States.
mutation in the QRDR of gyrA
Whole-genome comparative analysis of Campylobacter jejuni strains isolated from patients with diarrhea in northeastern Poland.
Present in all isolates
Molecular characterization of Campylobacter causing human clinical infection using whole-genome sequencing: Virulence, antimicrobial resistance and phylogeny in Ireland.
Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry.
Only mutations in the quinolone resistance-determining region (QRDR) of gyrA were regarded to be the determinants of resistance.
Hyper-Aerotolerant Campylobacter coli from Duck Sources and Its Potential Threat to Public Health: Virulence, Antimicrobial Resistance, and Genetic Relatedness.
Mutation in the quinolone resistance-determining region (QRDR) of gyrA conferring resistance to quinolones.
Comparison of different technologies for the decipherment of the whole genome sequence of Campylobacter jejuni BfR-CA-14430.
Point mutation in the gyrase subunit A conferring resistance against (fluoro-)quinolones.
Antimicrobial resistance patterns and molecular resistance markers of Campylobacter jejuni isolates from human diarrheal cases.
Prevalence, Population Diversity and Antimicrobial Resistance of Campylobacter coli Isolated in Italian Swine at Slaughterhouse.
Increasing prevalence of a fluoroquinolone resistance mutation amongst Campylobacter jejuni isolates from four human infectious intestinal disease studies in the United Kingdom.
The T86I mutation in gyrA is associated with fluoroquinolone resistance.
Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.
Overview of Ecology and Aspects of Antibiotic Resistance in Campylobacter spp. Isolated from Free-Grazing Chicken Tissues in Rural Households.
Integrative and Conjugative Elements and Prophage DNA as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains from Domestic Geese in Poland.
Characterization of antimicrobial resistance patterns and detection of virulence genes in Campylobacter isolates in Italy.
The mutation T86-I was found in 83 strains resistant to ciprofloxacin and/or nalidixic acid.
Investigating the host specificity of Campylobacter jejuni and Campylobacter coli by sequencing gyrase subunit A.
The Thr86Ile substitution in gyrA is associated with quinolone resistance.
Trends in fluoroquinolone resistance in Campylobacter.
Single point mutation in the gyrA gene within the QRDR is the most frequent mechanism of CIP resistance.
Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin.
Antimicrobial resistance mechanisms among Campylobacter.
The Thr86Ile mutation in gyrA is the most frequent mutation associated with fluoroquinolone resistance in Campylobacter.
Fluoroquinolone-Resistant Salmonella enterica, Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana.
Comparison of Antimicrobial Susceptibility Profiles of Thermotolerant Campylobacter spp. Isolated from Human and Poultry Samples in Georgia (Caucasus).
The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic.
Whole-genome-based characterization of Campylobacter jejuni from human patients with gastroenteritis collected over an 18 year period reveals increasing prevalence of antimicrobial resistance.
T86I is the most prevalent mutation in quinolone-resistant isolates
Genomic insight into Campylobacter jejuni isolated from commercial turkey flocks in Germany using whole-genome sequencing analysis.
associated with fluoroquinolone resistance
Antimicrobial resistance profiles of Campylobacter jejuni and Salmonella spp. isolated from enteritis patients in Japan.
Detected in 31 STs
Prevalence, genomic characterization and antimicrobial resistance of Campylobacter spp. isolates in pets in Shenzhen, China.
Genomic and Antimicrobial Surveillance of Campylobacter Population in Italian Poultry.
First Report of Campylobacter jejuni Strains Belonging to ST-21 Clonal Complex Isolated from Human, Poultry and Wild Birds in Croatia: Antimicrobial Resistance and Genetic Distance.
Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance Genes and Core-Genome Multilocus Sequence Typing of Campylobacter jejuni from Different Sources in Lithuania.
Vertebral osteomyelitis caused by Campylobacter jejuni in an immunocompetent patient.
Confers resistance to ciprofloxacin.
Campylobacter jejuni in hospitalized patients with diarrhea, Kolkata, India.
Virulence and Antimicrobial Resistance in Campylobacter spp. from a Peruvian Pediatric Cohort.
Subtype-Specific Selection for Resistance to Fluoroquinolones but Not to Tetracyclines Is Evident in Campylobacter jejuni Isolates from Beef Cattle in Confined Feeding Operations in Southern Alberta, Canada.
Mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene confer resistance to ciprofloxacin and nalidixic acid.
Prevalence of Genetic Determinants and Phenotypic Resistance to Ciprofloxacin in Campylobacter jejuni from Lithuania.
Acquisition of fluoroquinolone resistance leads to increased biofilm formation and pathogenicity in Campylobacter jejuni.
Additional mutations in gyrA (Asp90Asn) and gyrB (Leu458Lys) were observed in some ciprofloxacin-resistant strains.
Molecular Characterization and Antimicrobial Susceptibility of C. jejuni Isolates from Italian Wild Bird Populations.
Microevolution of Campylobacter jejuni during long-term infection in an immunocompromised host.
Mutations in gyrA contribute to fluoroquinolone resistance.
The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2016.
Point mutation in gyrA gene responsible for fluoroquinolone resistance.
Validation of the T86I mutation in the gyrA gene as a highly reliable real time PCR target to detect Fluoroquinolone-resistant Campylobacter jejuni.
Molecular characterization of Campylobacter spp. recovered from beef, chicken, lamb and pork products at retail in Australia.
Present in isolates from all sources except beef.
Campylobacter jejuni from Canine and Bovine Cases of Campylobacteriosis Express High Antimicrobial Resistance Rates against (Fluoro)quinolones and Tetracyclines.
associated with (fluoro)quinolone resistance
Investigation of Antimicrobial Susceptibilities and Resistance Genes of Campylobacter Isolates from Patients in Edirne, Turkey.
Mutation detected in all ciprofloxacin-resistant isolates
Virulence Profiling, Multidrug Resistance and Molecular Mechanisms of Campylobacter Strains from Chicken Carcasses in Tunisia.
Five centuries of genome evolution and multi-host adaptation of Campylobacter jejuni in Brazil.
Transmission of dominant strains of Campylobacter jejuni and Campylobacter coli between farms and retail stores in Ecuador: Genetic diversity and antimicrobial resistance.
Genetic Diversity, Virulence, and Antibiotic Resistance Determinants of Campylobacter jejuni Isolates in Romania.
Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.
gyrA
gyrA polymorphism in Campylobacter jejuni: detection of gyrA mutations in 162 C. jejuni isolates by single-strand conformation polymorphism and DNA sequencing.
gyrA
Two distinct mutations in gyrA lead to ciprofloxacin and nalidixic acid resistance in Campylobacter coli and Campylobacter jejuni isolated from chickens and beef cattle.
gyrA
Fluoroquinolone resistance in Campylobacter species from man and animals: detection of mutations in topoisomerase genes.
gyrA
Quantitative assessment and genomic profiling of Campylobacter dynamics in poultry processing: a case study in the United Arab Emirates integrated abattoir system.
gyrA
Analysis of gyrA mutations in quinolone-resistant and -susceptible Campylobacter jejuni isolates from retail poultry and human clinical isolates by non-radioactive single-strand conformation polymorphism analysis and DNA sequencing.
gyrA
Identification of the main quinolone resistance determinant in Campylobacter jejuni and Campylobacter coli by MAMA-DEG PCR.
Campylobacter jejuni gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003789
Serotypes, Antibiotic Susceptibility, Genotypic Virulence Profiles and SpaA Variants of Erysipelothrix rhusiopathiae Strains Isolated from Pigs in Poland.
Erysipelothrix rhusiopathiae gyrA with mutation conferring resistance to enrofloxacin; CARD accession: CARD:3007544
Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates.
Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp.
Multiplex strategy for multilocus sequence typing, fla typing, and genetic determination of antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolates collected in Switzerland.
mutation in gyrA confers quinolone resistance
Genomic Analysis and Antimicrobial Resistance of Campylobacter jejuni and Campylobacter coli in Peru.
Both mutations were found in C. jejuni and C. coli.
Emergence of a Potent Multidrug Efflux Pump Variant That Enhances Campylobacter Resistance to Multiple Antibiotics.
The C257T mutation in gyrA enhances fluoroquinolone resistance when combined with RE-cmeABC.
Genomic Characterization of Fluoroquinolone-Resistant Thermophilic Campylobacter Strains Isolated from Layer Chicken Feces in Gangneung, South Korea by Whole-Genome Sequencing.
Population Genetics and Antimicrobial Susceptibility of Canine Campylobacter Isolates Collected before and after a Raw Feeding Experiment.
Point mutation C257T in gyrA leads to Thr-86-Met substitution, causing reduced susceptibility to ciprofloxacin and nalidixic acid.
Antimicrobial Susceptibility Profiles of Human Campylobacter jejuni Isolates and Association with Phylogenetic Lineages.
Point mutations in gyrA confer resistance to fluoroquinolones.
Genotypes and antibiotic resistances of Campylobacter jejuni isolates from cattle and pigeons in dairy farms.
The C257T mutation in the gyrA gene leads to quinolone resistance.
Phenotypic and Genotypic Examination of Antimicrobial Resistance in Thermophilic Campylobacter Species Isolated from Poultry in Turkey.
Mutation in DNA gyrase subunit A responsible for quinolone resistance
Genomic Insights into the Increased Occurrence of Campylobacteriosis Caused by Antimicrobial-Resistant Campylobacter coli.
Genetic characteristics, antimicrobial susceptibility, and virulence genes distribution of Campylobacter isolated from local dual-purpose chickens in central China.
Should We Consider Them as a Threat? Antimicrobial Resistance, Virulence Potential and Genetic Diversity of Campylobacter spp. Isolated from Varsovian Dogs.
Prevalence and antimicrobial resistance of Campylobacter species in shelter-housed healthy and diarrheic cats and dogs in Turkey.
The Thr-86-Ile mutation was the most common change detected in the gyrA gene in the quinolone-resistant isolates.
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