ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemexD

efflux pump component

Protein ChangeS133G

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: multidrug efflux RND transporter permease subunit MexD
Resistance To: Ceftolozane/tazobactam|Ceftazidime-avibactam, AVIBACTAM
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Emergence of Resistance to Novel Cephalosporin–β-Lactamase Inhibitor Combinations through the Modification of the Pseudomonas aeruginosa MexCD-OprJ Efflux Pump.

PMID 34060900 · 2021

mexD

Mutation Information

mexD: p.S133G

Protein Change: S133G
Organisms: Pseudomonas aeruginosa
Confers Resistance To: Ceftolozane/tazobactam|Ceftazidime-avibactam

Browse AMR Mutations

Mutation Information