Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A Molecular Perspective on Colistin and Klebsiella pneumoniae: Mode of Action, Resistance Genetics, and Phenotypic Susceptibility.
Disruption of mgrB leads to upregulation of PhoP/PhoQ and constitutive activation of the arnBCADTEF operon and PmrA/PmrB via PmrD.
Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis.
Polymyxin-resistant hypervirulent Klebsiella pneumoniae clinical isolates from a tertiary hospital in China: molecular mechanisms, antimicrobial susceptibility, and virulent phenotypes.
Identified in the study and consistent with previous research.
MgrB inactivation is a common mechanism of colistin resistance in KPC-producing Klebsiella pneumoniae of clinical origin.
mgrB
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