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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations marRL46P

GenemarR

global regulator

Protein ChangeL46P

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss-of-function
Resistance To: Ampicillin|Tetracycline
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

The Atypical Antipsychotic Quetiapine Promotes Multiple Antibiotic Resistance in Escherichia coli.

PMID 35416690 · 2022

Mutations in marR were associated with increased expression of marA, acrA, and tolC, and reduced expression of ompF.

Mutation Information

Protein Change: L46P
Organisms: Escherichia coli
Confers Resistance To: Ampicillin|Tetracycline

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

loss-of-function

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research