Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations mcr-1S284D

colistin resistance protein

Protein ChangeS284D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Colistin
Organisms: E. coli
Papers: 1

Paper Information1

1

Sequence variation in the active site of mobile colistin resistance proteins is evolutionarily accommodated through inter-domain interactions.

PMID 39509206 · 2024

Wild-type MCR-1 increases the MIC of colistin by ~12-fold

Mutation Information

Protein Change: S284D
Organisms: E. coli
Confers Resistance To: Colistin
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research