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Browse Mutations gyrAL91P

GenegyrA

Protein ChangeL91P

Nucleotide ChangeT271C

Validation StatusConfirmed2+ DBs

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Overview

Resistance To: Fluoroquinolones, Ofloxacin|Moxifloxacin
Papers: 2

Paper Information2

Potential of nanopore sequencing for tuberculosis diagnosis and drug resistance detection.

PMID 39731145 · 2024

Mutation Information

gyrA: p.L91P / c.T271C

Protein Change: L91P
Nucleotide Change: T271C
Confers Resistance To: Fluoroquinolones

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

Sequence Analysis of Fluoroquinolone Resistance-Associated Genes gyrA and gyrB in Clinical Mycobacterium tuberculosis Isolates from Patients Suspected of Having Multidrug-Resistant Tuberculosis in New Delhi, India.

PMID 27335153 · 2016

Heterozygous mutations were observed in 4/27 (14.8%) mutations.

Mutation Information

gyrA: p.S91P / c.T271C

Protein Change: S91P
Nucleotide Change: T271C
Confers Resistance To: Ofloxacin|Moxifloxacin
Source Database: Reslit

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