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Browse Mutations porAD142H

GeneporA

pyruvate oxidoreductase

Protein ChangeD142H

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of calcium-binding site in channel
Resistance To: Ciprofloxacin
Organisms: Campylobacter jejuni
Papers: 1

Paper Information1

1

Campylobacter jejuni resistance to human milk involves the acyl carrier protein AcpP.

PMID 39998218 · 2025

Mutation in the calcium-binding site of PorA reduces ciprofloxacin permeability.

Mutation Information

Protein Change: D142H
Organisms: Campylobacter jejuni
Confers Resistance To: Ciprofloxacin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

loss of calcium-binding site in channel

Source Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research