ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp3

penicillin-binding protein

Protein ChangeV383Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Vancomycin
Papers: 1

Paper Information1

Discovery of amino acid substitutions in penicillin-binding proteins associated with adaptation to D-Ala-D-Lac in vancomycin-resistant Enterococcus faecalis.

PMID 40007607 · 2025

Multiple substitutions in PBP3 affect the active site and may influence substrate binding.

Mutation Information

pbp3: p.V383Y

Protein Change: V383Y
Confers Resistance To: Vancomycin
Source Database: Reslit

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