ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemexS

transcriptional repressor of MexEF-OprN efflux pump

Protein ChangeG123R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Imipenem|Relebactam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Effects of different mechanisms on antimicrobial resistance in Pseudomonas aeruginosa: a strategic system for evaluating antibiotics against gram-negative bacteria.

PMID 40042282 · 2025

MexS mutation was identified as a cause of resistance to imipenem and relebactam in a KPC-producing P. aeruginosa strain.

Mutation Information

mexS: p.G123R

Protein Change: G123R
Organisms: Pseudomonas aeruginosa
Confers Resistance To

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