GenegyrB
Protein ChangeD426N
Validation StatusConfirmed2+ DBs
Databases
ResFinderReslit
Overview
- Mechanism
- Target modification
- Resistance To
- Ciprofloxacin|Moxifloxacin, moxifloxacin|ciprofloxacin|gatifloxacin|levofloxacin, moxifloxacin|ciprofloxacin|levofloxacin|gatifloxacin, Nalidixic acid,Ciprofloxacin
- Organisms
- Clostridium difficile, Escherichia coli
- Papers
- 4
Paper Information4
1
gyrA and gyrB Mutations Are Implicated in Cross-Resistance to Ciprofloxacin and Moxifloxacin in Clostridium difficile.
Mutation Information
- Protein Change
- D426N
- Organisms
- Clostridium difficile
- Confers Resistance To
- Ciprofloxacin|Moxifloxacin
- Source Database
- Reslit
2
Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe.
Two new substitutions for C. difficile, Ser416Ala and Arg447Lys, were found in GyrB.
Mutation Information
- Protein Change
- D426N
- Organisms
- Clostridium difficile
- Confers Resistance To
- moxifloxacin|ciprofloxacin|gatifloxacin|levofloxacin
- Source Database
- Reslit
3
Clostridium difficile Isolates Resistant to Fluoroquinolones in Italy: Emergence of PCR Ribotype 018
Mutation in gyrB confers resistance to fluoroquinolones
Mutation Information
- Protein Change
- D426N
- Organisms
- Clostridium difficile
- Confers Resistance To
- moxifloxacin|ciprofloxacin|levofloxacin|gatifloxacin
- Source Database
- Reslit
4
Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli.
Mutation Information
- Protein Change
- D426N
- Organisms
- Escherichia coli
- Confers Resistance To
- Nalidixic acid,Ciprofloxacin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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