GenegyrB
Protein ChangeR447K
Validation StatusCandidate
Databases
Reslit
Overview
- Resistance To
- moxifloxacin|ciprofloxacin|levofloxacin, moxifloxacin|levofloxacin
- Organisms
- Clostridium difficile
- Papers
- 2
Paper Information2
1
Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe.
Two new substitutions for C. difficile, Ser416Ala and Arg447Lys, were found in GyrB.
Mutation Information
- Protein Change
- R447K
- Organisms
- Clostridium difficile
- Confers Resistance To
- moxifloxacin|ciprofloxacin|levofloxacin
- Source Database
- Reslit
2
Molecular analysis of the gyrA and gyrB quinolone resistance-determining regions of fluoroquinolone-resistant Clostridium difficile mutants selected in vitro.
Mutation Information
- Protein Change
- R447K
- Organisms
- Clostridium difficile
- Confers Resistance To
- moxifloxacin|levofloxacin
- Source Database
- Reslit
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