ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemdfA

efflux pump

Protein ChangeE26K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Chloramphenicol
Organisms: Escherichia coli
Papers: 1

Paper Information1

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA.

PMID 10022825 · 1999

The E26K mutation abolishes resistance to positively charged drugs but retains chloramphenicol resistance.

Mutation Information

mdfA: p.E26K

Protein Change: E26K
Organisms: Escherichia coli
Confers Resistance To: Chloramphenicol
Source Database: Reslit

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